The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 06, 2018

Filed:

Jul. 16, 2014
Applicant:

Verily Life Sciences Llc, Mountain View, CA (US);

Inventors:

Jerrod Joseph Schwartz, San Francisco, CA (US);

Mark Audeh, Mountain View, CA (US);

Vikram Singh Bajaj, Mountain View, CA (US);

Assignee:

Verily Life Sciences LLC, Mountain View, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/145 (2006.01); G01N 33/543 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
G01N 33/54346 (2013.01); A61B 5/145 (2013.01); A61B 5/14507 (2013.01); G01N 33/56966 (2013.01);
Abstract

A system for modulating a response signal includes polyvalent functionalized nanoparticles configured to bind with target analytes located on a surface of a cell, a detector configured to detect an analyte response signal transmitted from the body, a modulation source configured to modulate the analyte response signal, and a processor configured to non-invasively detect the one or more target analytes by differentiating the analyte response signal from a background signal, at least in part, based on the modulation. The analyte response signal is related to the binding interaction of the target analytes on the cell surface with the polyvalent functionalized nanoparticles. In some examples, the system may also include magnetic particles and a magnetic field source sufficient to distribute the magnetic particles into a spatial arrangement in the body. The analyte response signal may be differentiated from the background signal, at least in part, based on modulation of the signals due, at least in part, to the spatial arrangement of the magnetic particles.


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