The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 06, 2018

Filed:

Apr. 12, 2017
Applicant:

Butamax Advanced Biofuels Llc, Wilmington, DE (US);

Inventors:

Lori Ann Maggio-Hall, Wilmington, DE (US);

Brian James Paul, Wilmington, DE (US);

Steven Cary Rothman, Wilmington, DE (US);

Rick W. Ye, Hockessin, DE (US);

Assignee:

Butamax Advanced Biofuels LLC, Wilmington, DE (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 7/16 (2006.01); C12N 9/88 (2006.01); C12N 15/00 (2006.01); C12N 1/20 (2006.01); C07H 21/04 (2006.01); C12P 7/40 (2006.01);
U.S. Cl.
CPC ...
C12P 7/16 (2013.01); C12N 9/88 (2013.01); C12N 15/00 (2013.01); C12P 7/40 (2013.01); C12Y 402/01009 (2013.01);
Abstract

Dihydroxy-acid dehydratase (DHAD) variants that display increased DHAD activity are disclosed. Such enzymes can result in increased production of compounds from DHAD requiring biosynthetic pathways. Also disclosed are isolated nucleic acids encoding the DHAD variants, recombinant host cells comprising the isolated nucleic acid molecules, and methods of producing butanol.


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