The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 06, 2018

Filed:

Sep. 11, 2013
Applicants:

Vib Vzw, Ghent, BE;

Katholieke Universiteit Leuven K.u. Leuven R&d, Leuven, BE;

Vrije Universiteit Brussel, Brussels, BE;

Inventors:

Bart De Strooper, Leuven, BE;

Els Marjaux, Attenrode-Wever, BE;

Lujia Zhou, Leuven, BE;

Serge Muyldermans, Hoeilaart, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/40 (2006.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); C07K 2317/22 (2013.01); C07K 2317/565 (2013.01); C07K 2317/569 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract

Described are single domain antibodies with a specificity for BACE1. More specifically, described are single variable-domain antibodies derived from camelids that bind to BACE1 and are capable of inhibiting the activity of BACE1. The antibodies can be used for research and medical applications. Specific applications include the use of BACE1-specific antibodies for the treatment of Alzheimer's disease.


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