The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 06, 2018

Filed:

May. 31, 2013
Applicant:

Ablynx N.v., Zwijnaarde, BE;

Inventors:

Welbeck Owusu Danquah, Hamburg, DE;

Friedrich Nolte, Hamburg, DE;

Catelijne Stortelers, Ghent, BE;

Toon Laeremans, Dworp-Beersel, BE;

Assignees:

Ablynx N.V., Ghent-Zwijnaarde, BE;

University Medical Center Hamburg-Eppendorf, Hamburg, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C12N 5/10 (2006.01); C07K 14/705 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/28 (2013.01); A61K 2039/505 (2013.01); C07K 14/705 (2013.01); C07K 2317/21 (2013.01); C07K 2317/22 (2013.01); C07K 2317/565 (2013.01); C07K 2317/569 (2013.01); C07K 2317/64 (2013.01); C07K 2317/76 (2013.01);
Abstract

The present invention relates to biological materials against P2X7 and more in particular to polypeptides, nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to host cells expressing or capable of expressing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such polypeptides, for prophylactic, therapeutic or diagnostic purposes. In particular, the biological materials of the present invention inhibit the biological activity of the P2X7 receptor, such as activation by ATP.


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