The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 06, 2018
Filed:
Jun. 30, 2016
Applicants:
Michael Lin, Stanford, CA (US);
Jun Chu, Shenzhen, CN;
Younghee OH, Incheon, KR;
Inventors:
Assignee:
The Board of Trustees of the Leland Stanford Junior University, Palo Alto, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61K 49/00 (2006.01); C12Q 1/66 (2006.01); C12N 9/02 (2006.01); G01N 21/76 (2006.01); C07K 14/435 (2006.01); G01N 21/64 (2006.01); G01N 33/58 (2006.01);
U.S. Cl.
CPC ...
C07K 14/43595 (2013.01); A61B 5/0071 (2013.01); A61B 5/0082 (2013.01); A61K 49/0045 (2013.01); C12N 9/0069 (2013.01); C12Q 1/66 (2013.01); C12Y 113/12007 (2013.01); G01N 21/6428 (2013.01); G01N 21/6458 (2013.01); G01N 21/763 (2013.01); G01N 33/582 (2013.01); C07K 2319/60 (2013.01);
Abstract
Engineered orange-red fluorescent proteins with enhanced fluorescent properties, obtained by mutagenesis of mNeptune2, are disclosed. In particular, the invention relates to engineered orange-red fluorescent proteins excitable with cyan light having increased emission intensity and their use in bioluminescent resonance energy transfer systems and fluorescence and bioluminescence imaging.