The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 06, 2018
Filed:
Oct. 16, 2015
Applicant:
St. Jude Children's Research Hospital, Memphis, TN (US);
Inventors:
Assignee:
St. Jude Children's Research Hospital, Memphis, TN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/08 (2006.01); C07D 403/06 (2006.01); C07D 401/06 (2006.01); C07D 409/06 (2006.01); C07D 403/14 (2006.01); C07D 401/14 (2006.01); C07D 413/14 (2006.01); C07D 405/12 (2006.01); C07D 223/28 (2006.01); C07D 223/22 (2006.01);
U.S. Cl.
CPC ...
C07D 487/08 (2013.01); C07D 223/22 (2013.01); C07D 223/28 (2013.01); C07D 401/06 (2013.01); C07D 401/14 (2013.01); C07D 403/06 (2013.01); C07D 403/14 (2013.01); C07D 405/12 (2013.01); C07D 409/06 (2013.01); C07D 413/14 (2013.01);
Abstract
The compounds of the invention are antagonists of CAR, with specificity for CAR over other proteins including PXR. The disclosed compounds are useful in treating or controlling cell proliferative disorders, in particular oncological disorders, such as cancer. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.