The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 06, 2018

Filed:

Aug. 18, 2014
Applicant:

Duke University, Durham, NC (US);

Inventors:

Pei Zhou, Durham, NC (US);

Eric J. Toone, Durham, NC (US);

Robert A. Nicholas, Chapel Hill, NC (US);

Assignees:

Duke University, Durham, NC (US);

University of North Carolina Chapel Hill, Chapel Hill, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/445 (2006.01); C07D 211/08 (2006.01); C07D 211/06 (2006.01); C07D 211/14 (2006.01); A61K 31/455 (2006.01);
U.S. Cl.
CPC ...
C07D 211/06 (2013.01); C07D 211/14 (2013.01); A61K 31/455 (2013.01);
Abstract

Disclosed are compounds of formulae: (I) and pharmaceutically acceptable salts thereof, wherein the variables, R, R, Y, and Z are defined herein. These compounds are useful for treating Gram-negative bacteria infections.


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