The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 06, 2018
Filed:
Aug. 19, 2016
Applicant:
University of Virginia Patent Foundation, Charlottesville, VA (US);
Inventors:
Kevin R. Lynch, Charlottesville, VA (US);
Timothy L. Macdonald, Charlottesville, VA (US);
Thomas P. Mathews, Charlottesville, VA (US);
Andrew Kennedy, Charlottesville, VA (US);
Yugesh Kharel, Charlottesville, VA (US);
Assignee:
University of Virginia Patent Foundation, Charlottesville, VA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/40 (2006.01); C07D 207/09 (2006.01); C07C 257/16 (2006.01);
U.S. Cl.
CPC ...
C07D 207/09 (2013.01); A61K 31/40 (2013.01); C07C 257/16 (2013.01); C07C 2101/02 (2013.01); C07C 2101/08 (2013.01); C07C 2101/14 (2013.01); C07C 2103/74 (2013.01);
Abstract
Imidamide (amidine) analogs that can inhibit the activity of sphingosine kinase 1 and sphingosine kinase 2 (SphK1 & SphK2) are provided. The compounds can prevent angiogenesis in tumors.