The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 06, 2018
Filed:
Nov. 09, 2016
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Washington, DC (US);
Irving William Wainer, Washington, DC (US);
Weizhong Zhu, Philadelphia, PA (US);
Khalid Chakir, Baltimore, MD (US);
Rui-Ping Xiao, Baltimore, MD (US);
Darrell R. Abernethy, Annapolis, MD (US);
Farideh M. Beigi Abhari, Durham, NC (US);
Abstract
This disclosure concerns the discovery of (R,R)- and (R,S)-fenoterol analogs which are highly effective at binding β2-adrenergic receptors. Exemplary chemical structures for these analogs are provided. Also provided are pharmaceutical compositions including the disclosed (R,R)-fenoterol and fenoterol analogs, and methods of using such compounds and compositions for the treatment of cardiac disorders such as congestive heart failure and pulmonary disorders such as asthma or chronic obstructive pulmonary disease.