The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 06, 2018
Filed:
Sep. 22, 2015
Applicant:
Industry-academic Cooperation Foundation Yonsei University, Seoul, KR;
Inventors:
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); G01N 15/06 (2006.01); G01N 33/00 (2006.01); G01N 33/48 (2006.01); G01N 33/543 (2006.01); G01N 33/50 (2006.01); G01N 33/569 (2006.01); B01F 5/06 (2006.01); B01F 13/00 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502761 (2013.01); B01F 5/0647 (2013.01); B01F 5/0655 (2013.01); B01F 13/0059 (2013.01); B01L 3/502707 (2013.01); G01N 33/5002 (2013.01); G01N 33/5434 (2013.01); G01N 33/54326 (2013.01); G01N 33/54346 (2013.01); G01N 33/56972 (2013.01); B01L 3/5085 (2013.01); B01L 2200/0652 (2013.01); B01L 2200/0668 (2013.01); B01L 2300/044 (2013.01); B01L 2300/0858 (2013.01); B01L 2300/0883 (2013.01); B01L 2400/043 (2013.01); B01L 2400/0409 (2013.01); G01N 2333/70589 (2013.01);
Abstract
The present invention relates to a microfluidic separation device, a separation method using the same and a kit for separating circulating rare cells from blood using the same, and more particularly, to a microfluidic-based separation technology for fixing target particles of a sample, which have a specific affinity for magnetic nanoparticles, to a device by use of a magnetic material, and for isolating the sample from which the target particles have been removed. The present invention may be effectively applied to remove leukocytes from a blood sample in order to isolate circulating rare cells (CRCs), particularly circulating tumor cells (CTCs).