The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 06, 2018
Filed:
Apr. 28, 2016
Applicant:
Ewha University-industry Collaboration Foundation, Seoul, KR;
Inventor:
Kyunglim Lee, Seoul, KR;
Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/64 (2017.01); A61K 47/48 (2006.01); C07K 7/06 (2006.01); C07K 14/47 (2006.01); C07K 14/435 (2006.01); C07K 16/18 (2006.01); C07K 7/08 (2006.01); A61K 48/00 (2006.01); C07K 14/46 (2006.01); A61K 47/65 (2017.01);
U.S. Cl.
CPC ...
A61K 47/48246 (2013.01); A61K 47/64 (2017.08); A61K 47/65 (2017.08); A61K 48/0008 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01); C07K 14/435 (2013.01); C07K 14/46 (2013.01); C07K 14/47 (2013.01); C07K 16/18 (2013.01);
Abstract
Provided are transmembrane complexes that contain a protein transduction domain (PTD) from the N-terminus of IgE-dependent histamine-releasing factor (HRF) and a target substance that is to be delivered into a cell. Also provided are nucleic acid molecules encoding the transmembrane complex and methods of delivering the target substance into a cell interior by contacting the transmembrane complex with a cell. Also provided are transfection kits containing the PTD and the target substance.