The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 06, 2018
Filed:
Sep. 09, 2013
Applicant:
Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);
Inventors:
Mark A. Exley, Chestnut Hill, MA (US);
Lydia Lynch, Brookline, MA (US);
Donal O'Shea, Dublin, IE;
Cliona O'Farrelly, Wexford, IE;
Steven P. Balk, Needham, MA (US);
Assignee:
Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7032 (2006.01); A61K 45/06 (2006.01); A61K 39/395 (2006.01); A61K 31/70 (2006.01); A61K 35/17 (2015.01);
U.S. Cl.
CPC ...
A61K 39/3955 (2013.01); A61K 31/70 (2013.01); A61K 31/7032 (2013.01); A61K 35/17 (2013.01); A61K 45/06 (2013.01);
Abstract
The present invention relates to the discovery that increases in invariant NKT cell (iNKT) number and/or activity can reduce the incidence or severity of metabolic disorders such as obesity and diabetes. The invention accordingly features methods, kits, and compositions for the treatment of such metabolic disorders by administration of a composition capable of increasing iNKT activity.