The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 06, 2018
Filed:
Oct. 27, 2016
Applicant:
Scil Technology Gmbh, Martinsried, DE;
Inventors:
Klaus Hellerbrand, Moorenweis, DE;
Rainer Sigl, Puchheim, DE;
Assignee:
SCIL TECHNOLOGY GMBH, Martinsried, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/16 (2006.01); A61K 38/17 (2006.01); A61K 9/00 (2006.01); A61K 47/22 (2006.01); C07K 14/47 (2006.01); C07K 14/78 (2006.01); A61K 47/24 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1709 (2013.01); A61K 9/0019 (2013.01); A61K 47/22 (2013.01); A61K 47/24 (2013.01); C07K 14/4703 (2013.01); C07K 14/78 (2013.01); A61K 9/0024 (2013.01); A61K 38/00 (2013.01);
Abstract
The present invention relates to stable aqueous formulations comprising at least 5 mg/mL CD-RAP and a charged amino acid, said amino acid preferably having a net charge at a pH between about 6 and 8. The ingredients of the formulation preferably provide stability over repeated freeze-thaw cycles. In a preferred aspect, the formulation is for use in therapy, preferably for use in the treatment of inflammatory disorders, preferably osteoarthritis. Furthermore, a kit comprising the formulation of the invention is provided.