The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 06, 2018

Filed:

Jun. 20, 2013
Applicant:

The University of Vermont and State Agricultural College, Burlington, VT (US);

Inventors:

Yvonne M. Janssen-Heininger, Charlotte, VT (US);

Vikas Anathy, Essex Junction, VT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/43 (2006.01); A61K 38/12 (2006.01); A61K 38/06 (2006.01); A61K 38/16 (2006.01); A61K 38/45 (2006.01); A61K 45/06 (2006.01); A61K 31/425 (2006.01); A61K 31/437 (2006.01); C12N 15/113 (2010.01); A61K 31/197 (2006.01); A61K 31/713 (2006.01);
U.S. Cl.
CPC ...
A61K 38/12 (2013.01); A61K 31/197 (2013.01); A61K 31/425 (2013.01); A61K 31/437 (2013.01); A61K 31/713 (2013.01); A61K 38/06 (2013.01); A61K 38/164 (2013.01); A61K 38/45 (2013.01); A61K 45/06 (2013.01); C12N 15/113 (2013.01); C12N 15/1137 (2013.01); C12N 2310/14 (2013.01); C12Y 205/01018 (2013.01); C12Y 503/04001 (2013.01);
Abstract

The present invention generally relates to systems and methods for treating certain oxidative stress conditions. In one aspect, compositions and methods of the invention can be used to treat a subject having an oxidative stress condition, for example, a subject having pulmonary fibrosis. In some embodiments, an inhibitor of ERp57 (for example, thiomuscimol) and/or an inhibitor of GSTP (for example, TLK-199) may be used to treat the subject. Also provided in certain aspects of the present invention are kits for such therapies, methods for promoting such therapies, and the like.


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