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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9907811 B1

PDFFull Text
Date of Patent:
Mar. 06, 2018

Filed:

Mar. 18, 2016

Concentrated natamycin suspension formulations

Applicant:

Valent Biosciences Corporation, Libertyville, IL (US);

Inventors:

Zhengyu Huang, Buffalo Grove, IL (US);

Benjamin A. Belkind, Wilmette, IL (US);

Ayyappan Nair, Des Plaines, IL (US);

Gregory D. Venburg, Deerfield, IL (US);

Robert Fassel, Naches, WA (US);

Yong-Ki Kim, Yakima, WA (US);

Assignee:

VALENT BIOSCIENCES CORPORATION, Libertyville, IL (US);

Attorney:

Wood, Phillips, Katz, Clark & Mortimer

Primary Examiner:

Tracy Liu

Int. Cl.
CPC ...
A01N 43/653 (2006.01); A01N 53/00 (2006.01); A01N 41/10 (2006.01); A01N 25/04 (2006.01); A61K 31/7048 (2006.01); A61K 9/10 (2006.01); A01N 43/90 (2006.01); A61K 47/10 (2017.01); A61K 47/32 (2006.01); A61K 47/20 (2006.01); A61K 47/26 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7048 (2013.01); A01N 43/90 (2013.01); A61K 9/10 (2013.01); A61K 47/10 (2013.01); A61K 47/20 (2013.01); A61K 47/26 (2013.01); A61K 47/32 (2013.01);
Abstract

The present invention generally relates to concentrated natamycin suspension formulations for inhibition of fungal growth. Specifically, the present invention relates to stable suspension concentrate formulations comprising from about 25% to about 48% w/w natamycin, from about 0.1% to about 10% w/w of an anionic surfactant selected from the group consisting of polyelectrolyte polymers, modified styrene acrylic polymers, dioctyl sodium sulfosuccinates, sodium salts of naphthalene sulfonates, and combinations thereof, and water. The formulations of the present invention contain natamycin as particles which are on average less than 11 microns in diameter and the formulations have a viscosity of less than 1400 centipoise at 21 degrees Celsius.

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