The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 27, 2018

Filed:

Jul. 15, 2015
Applicant:

Temple University of the Commonwealth System of Higher Education, Philadelphia, PA (US);

Inventors:

Frank N. Chang, Dresher, PA (US);

George P. Tuszynski, Pittsgrove, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); G01N 33/563 (2006.01); G01N 33/577 (2006.01); C07K 16/40 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57488 (2013.01); C07K 16/40 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/34 (2013.01); C07K 2317/76 (2013.01); G01N 2333/902 (2013.01); G01N 2333/908 (2013.01); G01N 2800/52 (2013.01);
Abstract

An embodiment of the invention relates to the use of stabilized cancer peptide fragments derived from 'redoxin proteins' selected from the group consisting of thioredoxin; peroxiredoxin-1, 2 and 3; glutaredoxin-3; glutathione peroxidase-4; and nucleoredoxins for the diagnosis of cancers, particularly pancreatic cancer. A method for the detection of cancer, severity of cancer, and/or effectiveness of a therapeutic regimen comprises detecting and/or measuring the amount of redoxin peptide fragments present in the biological sample of a subject.


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