The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 27, 2018
Filed:
Aug. 05, 2013
Applicant:
Sab, Llc, Sioux Falls, SD (US);
Inventors:
Yoshimi Kuroiwa, La Jolla, CA (US);
Hiroaki Matsushita, Sioux Falls, SD (US);
Akiko Sano, Kanagawa pref, JP;
Assignee:
SAB, LLC, Sioux Falls, SD (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/85 (2006.01); C07H 21/02 (2006.01); C12P 21/00 (2006.01); A01K 67/027 (2006.01); C07K 16/12 (2006.01); C07K 16/00 (2006.01); C07K 16/46 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8509 (2013.01); A01K 67/0278 (2013.01); C07K 16/00 (2013.01); C07K 16/462 (2013.01); A01K 2207/15 (2013.01); A01K 2217/072 (2013.01); A01K 2217/075 (2013.01); A01K 2227/101 (2013.01); A01K 2267/01 (2013.01); C12N 2015/8518 (2013.01); C12N 2800/208 (2013.01);
Abstract
The invention relates to large-scale production of human antibodies by transgenic animals with high production of fully human IgG up to >10 g/L in sera with human IgG1 subclass dominancy. This invention also supports a feasibility of complex chromosome engineering for complicated genetic studies in non-murine mammalian species.