The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 27, 2018

Filed:

Sep. 12, 2014
Applicant:

Purdue Pharma L.p., Stamford, CT (US);

Inventor:

Mark Youngman, North Wales, PA (US);

Assignee:

Purdue Pharma L.P., Stamford, CT (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4375 (2006.01); C07D 471/08 (2006.01); C07D 471/18 (2006.01); C07B 59/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/18 (2013.01); C07B 59/002 (2013.01); C07B 2200/05 (2013.01);
Abstract

The application is directed to Pyridone-sulfone morphinan analogs compounds of Formula I: or pharmaceutically acceptable salts and solvates thereof, wherein ==, R1, R2, R3, R4 and Z are as defined as set forth in the specification. The invention is also directed to use of the compounds of Formula I or the pharmaceutically acceptable salts and solvates thereof to treat disorders responsive to the odulation of one or more opioid receptors, or as synthetic intermediates. Certain compounds of the present invention are especially useful for treating pain.


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