The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 27, 2018

Filed:

Dec. 19, 2014
Applicant:

Sunshine Lake Pharma Co., Ltd., Dongguan, Guangdong, CN;

Inventors:

Jiancun Zhang, Dongguan, CN;

Xiaojun Wang, Dongguan, CN;

Yingjun Zhang, Dongguan, CN;

Runfeng Lin, Dongguan, CN;

Yi Yu, Dongguan, CN;

Liang Chen, Dongguan, CN;

Jihua Lin, Dongguan, CN;

Assignee:

SUNSHINE LAKE PHARMA CO., LTD., Dongguan, Guangdong, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/10 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); C07D 409/14 (2006.01); C07D 417/14 (2006.01); C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/10 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01);
Abstract

The present invention relates to the field of medicine, provided herein are novel nitrogenous heterocyclic compounds, their preparation methods and their uses as drugs, especially for treatment and prevention of tissue fibrosis. Also provided herein are pharmaceutically acceptable compositions comprising the nitrogenous heterocyclic compounds and the uses of the compositions in the treatment of human or animal tissue fibrosis, especially for human or animal renal interstitial fibrosis, glomerular sclerosis, liver fibrosis, pulmonary fibrosis, IPF, peritoneal fibrosis, myocardial fibrosis, dermatofibrosis, postsurgical adhesion, benign prostatic hyperplasia, skeletal muscle fibrosis, scleroderma, multiple sclerosis, pancreatic fibrosis, cirrhosis, myosarcoma, neurofibroma, pulmonary interstitial fibrosis, diabetic nephropathy, alzheimer disease or vascular fibrosis.


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