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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9902710 B1

PDFFull Text
Date of Patent:
Feb. 27, 2018

Filed:

Oct. 16, 2015

Substituted 6, 7-dialkoxy-3-isoquinoline derivatives as inhibitors of phosphodiesterase 10 (pde 10a)

Applicant:

Allergan, Inc., Irvine, CA (US);

Inventors:

Bertrand Leblond, Paris, FR;

Thierry Taverne, St. Martin les Boulogne sur Mer, FR;

Cedric Chauvignac, Nogent sur Marne, FR;

Eric Beausoleil, Paris, FR;

Anne-Sophie Casagrande, Draveli, FR;

Laurent Desire, Paris, FR;

Matthew P. Pando, Paris, FR;

John E. Donello, Dana Point, CA (US);

Rong Yang, Mission Viejo, CA (US);

Assignees:

EXONHIT THERAPEUTICS, SA, Paris, FR;

ALLERGAN, INC., Irvine, CA (US);

Attorney:

Jonathan Bass

Primary Examiner:

Timothy R Rozof

Int. Cl.
CPC ...
C07D 217/02 (2006.01); C07D 217/04 (2006.01); C07D 401/06 (2006.01); C07D 401/14 (2006.01); C07D 405/06 (2006.01); C07D 409/06 (2006.01); C07D 413/06 (2006.01); C07D 471/04 (2006.01); C07D 491/056 (2006.01); C07F 9/62 (2006.01); C07F 9/6558 (2006.01);
U.S. Cl.
CPC ...
C07D 401/06 (2013.01); C07D 217/02 (2013.01); C07D 217/04 (2013.01); C07D 401/14 (2013.01); C07D 405/06 (2013.01); C07D 409/06 (2013.01); C07D 413/06 (2013.01); C07D 471/04 (2013.01); C07D 491/056 (2013.01); C07F 9/62 (2013.01); C07F 9/65583 (2013.01);
Abstract

The invention relates to compounds of the formula or a pharmaceutically acceptable salt thereof, wherein R', Rthrough Rand Ar are as defined herein. These compounds are useful as inhibitors of phosphodiesterase 10 (PDE10A) which are useful in treating central nervous system diseases such as psychosis and also in treating, for example, obesity, type II diabetes, metabolic syndrome, glucose intolerance, pain and ophthalmic diseases.

Find Patent Forward Citations

Leblond, Bertrand. (2018). Substituted 6, 7-dialkoxy-3-isoquinoline derivatives as inhibitors of phosphodiesterase 10 (pde 10a) (U.S. Patent No. 9902710). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9902710

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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