The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 27, 2018
Filed:
Dec. 30, 2014
Peking University Founder Group Co., Ltd., Beijing, CN;
Pkucare Pharmaceutical R&d Center, Beijing, CN;
Pku Healthcare Industry Group Co., Ltd., Beijing, CN;
Chongqin Yi, Beijing, CN;
Heng Xu, Beijing, CN;
Jing Tao, Beijing, CN;
Songwen Lin, Beijing, CN;
Fangbin Han, Beijing, CN;
PEKING UNIVERSITY FOUNDER GROUP CO., LTD., Beijing, CN;
PKUCARE PHARMACEUTICAL R & D CENTER, Beijing, CN;
PKU HEALTHCARE INDUSTRY GROUP CO., LTD., Beijing, CN;
Abstract
The present invention provides a polysubstituted pyridine compound of Formula I, a preparation method, a use and a pharmaceutical composition thereof. The polysubstituted pyridine compound of Formula I according to the present invention has an excellent anti-tumor effect, can inhibit various cell kinases simultaneously, has significantly excellent pharmacokinetic characteristics, and is very suitable for oral and intravenous administration. The pharmaceutical composition according to the present invention can be useful for treating tumors and cancers.