The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 27, 2018
Filed:
Feb. 28, 2014
Applicant:
Immunogen, Inc., Waltham, MA (US);
Inventor:
Wayne C. Widdison, Belmont, MA (US);
Assignee:
IMMUNOGEN, INC., Waltham, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/535 (2006.01); A61K 47/48 (2006.01); A61K 31/5365 (2006.01); C07D 403/06 (2006.01); C07D 403/12 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48384 (2013.01); A61K 31/5365 (2013.01); A61K 47/48569 (2013.01); C07D 403/06 (2013.01); C07D 403/12 (2013.01);
Abstract
The invention provides linker compounds and cytotoxic compounds that are useful for forming a CBA-drug conjugates; and conjugates so formed. Such conjugates and/or cytotoxic compounds may be effective for treating a range of diseases, such as cancer, with a relatively high activity at a relatively low, non-toxic dose.