The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 27, 2018

Filed:

Dec. 20, 2012
Applicant:

Vaccibody As, Oslo, NO;

Inventors:

Ole Henrik Brekke, Oslo, NO;

Agnete Brunsvik Fredriksen, Raelingen, NO;

Ali Areffard, Oslo, NO;

Mona Mari Lindeberg, Oslo, NO;

Assignee:

Vaccibody AS, Oslo, NO;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); C07K 14/025 (2006.01); A61K 39/395 (2006.01); A61K 39/00 (2006.01); C07K 14/52 (2006.01); C07K 14/005 (2006.01); C07K 16/08 (2006.01); C12N 7/00 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39575 (2013.01); A61K 39/0011 (2013.01); A61K 39/12 (2013.01); C07K 14/005 (2013.01); C07K 14/523 (2013.01); C07K 16/084 (2013.01); C12N 7/00 (2013.01); A61K 48/00 (2013.01); A61K 2039/505 (2013.01); A61K 2039/53 (2013.01); A61K 2039/585 (2013.01); A61K 2039/6031 (2013.01); A61K 2039/6056 (2013.01); A61K 2039/64 (2013.01); C07K 2317/526 (2013.01); C07K 2317/53 (2013.01); C07K 2319/00 (2013.01); C07K 2319/02 (2013.01); C07K 2319/30 (2013.01); C07K 2319/735 (2013.01); C12N 2710/20022 (2013.01); C12N 2710/20034 (2013.01); C12N 2710/20071 (2013.01); C12N 2800/22 (2013.01);
Abstract

The present invention relates to therapeutic compounds, such as vaccines against human papillomavirus (HPV) and in particular to DNA vaccines against HPV16 or HPV18. The invention further relates to protein construct encoding homodimeric peptides, which peptides may be released from a DNA vaccine or used separately. Further described are pharmaceutical formulations, host cells and methods for producing the vaccines, as well as methods for the treatment of various HPV induced diseases, such as cancers and infectious diseases by application.


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