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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9901622 B1

PDFFull Text
Date of Patent:
Feb. 27, 2018

Filed:

Jan. 13, 2015

Rapid action insulin formulations and pharmaceutical delivery systems

Applicant:

Thermalin Diabetes, Llc, Waban, MA (US);

Inventors:

Jeffrey I. Joseph, Penn Valley, PA (US);

Richard William Berenson, Waban, MA (US);

Bruce Frank, Indianapolis, IN (US);

Michael A. Weiss, Moreland Hills, OH (US);

Thomas Hattier, Cleveland Heights, OH (US);

Gregory Dubé, Littleton, MA (US);

Zhiqiang Chen, Cleveland, OH (US);

Assignee:

THERMALIN DIABETES, INC., Waban, MA (US);

Attorney:

Morgan Lewis & Bockius LLP

Primary Examiner:

Marcela M Cordero Garcia

Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/28 (2006.01); A61K 9/00 (2006.01); A61K 36/05 (2006.01); A61K 36/23 (2006.01); A61K 47/18 (2017.01); A61K 45/06 (2006.01); A61K 47/12 (2006.01); A61K 47/20 (2006.01); A61K 47/36 (2006.01); A61M 5/142 (2006.01); A61M 5/172 (2006.01); A61M 25/02 (2006.01); A61M 37/00 (2006.01); A61N 1/04 (2006.01); A61N 1/32 (2006.01); A61N 7/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/28 (2013.01); A61K 9/0019 (2013.01); A61K 9/0021 (2013.01); A61K 36/05 (2013.01); A61K 36/23 (2013.01); A61K 45/06 (2013.01); A61K 47/12 (2013.01); A61K 47/183 (2013.01); A61K 47/20 (2013.01); A61K 47/36 (2013.01); A61M 5/142 (2013.01); A61M 5/1723 (2013.01); A61M 25/02 (2013.01); A61M 37/0092 (2013.01); A61N 1/0448 (2013.01); A61N 1/327 (2013.01); A61N 7/00 (2013.01); A61M 2025/0253 (2013.01); A61M 2037/0007 (2013.01); A61M 2205/055 (2013.01); A61M 2205/35 (2013.01); A61M 2205/50 (2013.01); A61M 2205/502 (2013.01); A61M 2230/201 (2013.01);
Abstract

The present invention provides rapid-acting insulin and insulin analog formulations. The invention further provides delivery devices, particularly infusion sets, which allow for the rapid absorption of insulin and insulin analogs, as well as other active agents. Methods of using the insulin and insulin analog formulations as well as the insulin delivery devices for treating subjects with diabetes mellitus are also provided.

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