The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 27, 2018

Filed:

Mar. 31, 2016
Applicant:

Hanmi Pharm. Co., Ltd., Hwaseong-si, Gyeonggi-do, KR;

Inventors:

Sung Youb Jung, Suwon-si, KR;

Jin-Sun Kim, Yongin-si, KR;

Myung Hyun Jang, Seoul, KR;

Sang Hyun Lee, Seoul, KR;

In Young Choi, Yongin-si, KR;

Se Chang Kwon, Seoul, KR;

Assignee:

Hanmi Pharm. Co., Ltd., Hwaseong-Si, Gyeonggi-Do, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/22 (2006.01); A61K 47/48 (2006.01); A61K 38/26 (2006.01); C07K 14/605 (2006.01); A61P 3/06 (2006.01); A61K 45/06 (2006.01); C07K 14/76 (2006.01); C07K 14/78 (2006.01); A61K 47/60 (2017.01); A61K 47/59 (2017.01); A61K 47/64 (2017.01); A61K 47/68 (2017.01);
U.S. Cl.
CPC ...
A61K 38/26 (2013.01); A61K 38/22 (2013.01); A61K 45/06 (2013.01); A61K 47/59 (2017.08); A61K 47/593 (2017.08); A61K 47/60 (2017.08); A61K 47/643 (2017.08); A61K 47/6435 (2017.08); A61K 47/68 (2017.08); A61K 47/6811 (2017.08); C07K 14/605 (2013.01); C07K 14/76 (2013.01); C07K 14/78 (2013.01);
Abstract

The present invention relates to a composition for preventing or treating hyperlipidemia, fatty liver disease or arteriosclerosis, comprising an oxyntomodulin derivative as an active ingredient. The oxyntomodulin derivative has a high ability to activate GLP-1 receptor and glucagon receptor compared to native oxyntomodulin and has the effects of reducing the blood total cholesterol, low-density cholesterol and triglyceride levels that were increased by high-fat diet, and increasing high-density cholesterol levels and the high-density cholesterol/low-density cholesterol ratio. Thus, the oxyntomodulin derivative can be effectively used for the treatment of hyperlipidemia and related diseases.


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