The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 27, 2018

Filed:

Jun. 29, 2015
Applicant:

Delmar Pharmaceuticals, Inc., Vancouver, CA;

Inventor:

Dennis M. Brown, Menlo Park, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/045 (2006.01); A61K 31/336 (2006.01); A61K 33/24 (2006.01); A61K 45/06 (2006.01); A61K 31/4741 (2006.01); A61K 31/353 (2006.01); A61K 31/513 (2006.01); C07D 303/14 (2006.01); A61K 31/7088 (2006.01); A61K 38/19 (2006.01); A61K 31/12 (2006.01); A61K 31/155 (2006.01); A61K 31/216 (2006.01); A61K 31/352 (2006.01); A61K 31/4745 (2006.01); A61K 31/475 (2006.01); A61K 31/713 (2006.01); A61K 9/00 (2006.01); A61K 31/45 (2006.01);
U.S. Cl.
CPC ...
A61K 31/336 (2013.01); A61K 9/0019 (2013.01); A61K 31/12 (2013.01); A61K 31/155 (2013.01); A61K 31/216 (2013.01); A61K 31/352 (2013.01); A61K 31/353 (2013.01); A61K 31/475 (2013.01); A61K 31/4741 (2013.01); A61K 31/4745 (2013.01); A61K 31/513 (2013.01); A61K 31/7088 (2013.01); A61K 31/713 (2013.01); A61K 33/24 (2013.01); A61K 38/19 (2013.01); A61K 45/06 (2013.01); C07D 303/14 (2013.01); A61K 31/45 (2013.01);
Abstract

The present invention describes methods and compositions for improving the therapeutic efficacy of therapeutic agents previously limited by suboptimal therapeutic performance by either improving efficacy as monotherapy or reducing side effects. Such methods and compositions are particularly applicable to substituted hexitols such as dianhydrogalactitol and diacetyldianhydrogalactitol.


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