The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 27, 2018
Filed:
Mar. 09, 2016
Sbi Pharmaceuticals Co., Ltd., Minato-ku, Tokyo, JP;
National Center for Child Health and Development, Setagaya-ku, Tokyo, JP;
Ko Rii, Tokyo, JP;
Kiwamu Takahashi, Tokyo, JP;
Naomi Haga, Tokyo, JP;
Fuminori Abe, Tokyo, JP;
Tohru Tanaka, Tokyo, JP;
Motowo Nakajima, Minato-ku, JP;
Hidenori Ito, Minato-ku, JP;
National Center for Child Health and Development, Tokyo, JP;
SBI Pharmaceuticals Co., Ltd., Tokyo, JP;
Abstract
The present invention provides an agent for promoting graft survival which can suppress rejection without use of existing immunosuppressants, an organ preservation solution capable of maintaining the freshness of an organ excised from a donor, and the like. An agent for promoting graft survival or an organ preservation solution is prepared, which comprises 5-aminolevulinic acid (ALA) or a derivative thereof, or a salt of ALA or the derivative and an iron compound as active ingredients. Preferable examples of the ALAs can include ALA and various esters such as methyl ester, ethyl ester, propyl ester, butyl ester, and pentyl ester of ALA, and their hydrochlorides, phosphates, and sulfates. Preferable examples of the iron compound can include sodium ferrous citrate.