The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 27, 2018

Filed:

Mar. 14, 2012
Applicants:

Collin J. Weber, Atlanta, GA (US);

Susan A. Safley, Decatur, GA (US);

Kereen S. Gordon, Alpharetta, GA (US);

Nicholas E. Simpson, Alachua, FL (US);

Inventors:

Collin J. Weber, Atlanta, GA (US);

Susan A. Safley, Decatur, GA (US);

Kereen S. Gordon, Alpharetta, GA (US);

Nicholas E. Simpson, Alachua, FL (US);

Assignee:

EMORY UNIVERSITY, Atlanta, GA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/48 (2006.01); A61K 35/39 (2015.01); A61K 47/69 (2017.01);
U.S. Cl.
CPC ...
A61K 9/4891 (2013.01); A61K 35/39 (2013.01); A61K 47/6925 (2017.08);
Abstract

This disclosure relates to compositions and methods for encapsulating biomaterials such as cells to prevent immune responses. In certain embodiments, the disclosure relates to capsules comprising a cell or cells gelled in alginate coated with a layer that prevents migration of immune molecules to the cell surface and an outer capsule layer comprising non-immunogenic material optionally containing immunosuppressive agents. In certain embodiments, the cells are capable of generating insulin that emanates from the capsule.


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