The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 20, 2018

Filed:

Sep. 19, 2013
Applicant:

Thermo Electron Manufacturing Limited, Altrincham, GB;

Inventor:

Harald Ritchie, Chester, GB;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 30/60 (2006.01); B01D 15/20 (2006.01); G01N 30/52 (2006.01); B01J 20/28 (2006.01); B01J 20/283 (2006.01); B01J 20/10 (2006.01);
U.S. Cl.
CPC ...
G01N 30/60 (2013.01); B01D 15/20 (2013.01); B01J 20/103 (2013.01); B01J 20/283 (2013.01); B01J 20/28004 (2013.01); B01J 20/28052 (2013.01); B01J 20/28057 (2013.01); G01N 30/52 (2013.01); G01N 30/6069 (2013.01); B01J 2220/58 (2013.01); G01N 30/6039 (2013.01); G01N 2030/524 (2013.01);
Abstract

A chromatography column () containing a bed of packed particles (), wherein the packed particles comprise fused core particles and the particle diameters of the packed particles vary along the column. Preferably, the particles () are arranged according to their average particle diameter, in order of increasing average particle diameter from the inlet end () to the outlet end (). The bed may comprise a plurality of bed sections and each bed section has an average particle diameter calculated from the particles in that section and there are at least two different average particle diameter bed sections, wherein the particles of each bed are separated from particles of an adjacent bed by a partition that is liquid permeable to allow through a flow of mobile phase. A high column efficiency can be provided with lower pressure drop per unit length of the column.


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