The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 20, 2018
Filed:
Apr. 25, 2012
Julie Kan, San Diego, CA (US);
Stuart Thomson, Port Washington, NY (US);
Gretchen M. Argast, Farmingdale, NY (US);
Matthew E. O'connor, Massapequa Park, NY (US);
Murray Robinson, Boston, MA (US);
Bin Feng, North Reading, MA (US);
Joerg Heyer, Newton, MA (US);
Maria I. Chiu, Newton Centre, MA (US);
Richard Nicoletti, South Borough, MA (US);
Julie Kan, San Diego, CA (US);
Stuart Thomson, Port Washington, NY (US);
Gretchen M. Argast, Farmingdale, NY (US);
Matthew E. O'Connor, Massapequa Park, NY (US);
Murray Robinson, Boston, MA (US);
Bin Feng, North Reading, MA (US);
Joerg Heyer, Newton, MA (US);
Maria I. Chiu, Newton Centre, MA (US);
Richard Nicoletti, South Borough, MA (US);
OSI Pharmaceuticals, LLC, Farmingdale, NY (US);
AVEO PHARMACEUTICALS, INC., Cambridge, MA (US);
Abstract
The present invention provides diagnostic methods for assessing the EMT status of tumor cells, and for predicting the effectiveness of treatment of a cancer patient with an EGFR or IGF-1R kinase inhibitor, utilizing an EMT gene signature index score. The present invention further provides methods for treating patients with cancer that incorporate these methods.