The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 20, 2018
Filed:
Aug. 31, 2012
Stuart Pickering-brown, Manchester, GB;
Bryan Traynor, Bethesda, MD (US);
Andrew B. Singleton, Poolesville, MD (US);
Huw Morris, Cardiff, GB;
Peter Heutink, Tübingen, DE;
John Hardy, Chelmsford, GB;
Pentti Tienari, Helsinki, FI;
Stuart Pickering-Brown, Manchester, GB;
Bryan Traynor, Bethesda, MD (US);
Andrew B. Singleton, Poolesville, MD (US);
Huw Morris, Cardiff, GB;
Peter Heutink, Tübingen, DE;
John Hardy, Chelmsford, GB;
Pentti Tienari, Helsinki, FI;
The University of Manchester, Manchester, GB;
National Institute of Aging, Bethesda, MD (US);
Hospital District of Helsinki and UUSIMAA, Helsinki, FI;
VU University Medical Centre Armsterdam, Amsterdam, NL;
UCL Business PLC, London, GB;
University College Cardiff Consultants Limited, Cardiff, GB;
Abstract
The present invention relates to methods of assessing whether a subject has or is likely to develop a neurodegenerative disease comprising determining whether the subject has a mutation in the C9orf72 gene wherein said mutation prevents or disrupts C9orf72 expression relative to expression in a reference from subjects without the mutation.