The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 20, 2018
Filed:
Oct. 22, 2013
Agresearch Limited, Hamilton, NZ;
National Research Council of Canada (Nrc), Ottawa, CA;
Nicholas John Roberts, Feilding, NZ;
Amy Christina Curran, San Diego, CA (US);
Somrutai Winichayakul, Palmerston North, NZ;
Marissa Roldan, Palmerston North, NZ;
Richard William Scott, Palmerston North, NZ;
David Charles Taylor, Saskatoon, CA;
Elizabeth-France Marillia, Asquith, CA;
Agresearch Limited, Hamilton, NZ;
National Research Council of Canada, Ottawa, CA;
Abstract
The invention provides chimeric DGAT1 proteins comprising: a) at their N-terminal ends, an N-terminal portion of a first DGAT1 protein, and b) at their C-terminal ends, a C-terminal portion of a second DGAT1 protein. The chimeric DGAT proteins show enhanced activity relative to at least one of the first DGAT1 protein and the second DGAT1 protein. The chimeric DGAT proteins of the invention can be expressed in cells to increase cellular lipid accumulation and/or modify the cellular lipid profile. The invention also provides polynucleotides encoding the chimeric DGAT1 proteins, cells and compositions comprising the polynucleotides or chimeric DGAT1 proteins, and methods using the chimeric DGAT1 proteins to produce oil.