The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 20, 2018
Filed:
Jul. 29, 2015
Applicants:
University of Massachusetts, Boston, MA (US);
Firefly Bioworks, Cambridge, MA (US);
Inventors:
Victor Ambros, Hanover, NH (US);
Rosalind Lee, Hanover, NH (US);
Anthony Patrick Fusco, Westwood, MA (US);
Assignees:
University of Massachusetts, Boston, MA (US);
Firefly BioWorks, Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/34 (2006.01); C12N 15/10 (2006.01); C12Q 1/68 (2018.01);
U.S. Cl.
CPC ...
C12N 15/1013 (2013.01); C12N 15/1006 (2013.01); C12N 15/1017 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/6883 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/178 (2013.01);
Abstract
Methods for isolating circulating small RNAs, e.g., microRNA (miRNA), from plasma samples, e.g., that comprise using an alkaline phenol:chloroform extraction, and methods of use thereof, including for the detection, prognosis, and/or monitoring of disease in a subject.