The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 20, 2018

Filed:

Sep. 30, 2015
Applicants:

Zhemin Zhou, Wuxi, CN;

Wenjing Cui, Wuxi, CN;

Zhongmei Liu, Wuxi, CN;

LI Zhou, Wuxi, CN;

Yuanyuan Xia, Wuxi, CN;

Inventors:

Zhemin Zhou, Wuxi, CN;

Wenjing Cui, Wuxi, CN;

Zhongmei Liu, Wuxi, CN;

Li Zhou, Wuxi, CN;

Yuanyuan Xia, Wuxi, CN;

Assignee:

Jiangnan University, Wuxi, JS, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/88 (2006.01); C12N 15/00 (2006.01); C12P 13/02 (2006.01); C07H 21/04 (2006.01); C12P 21/04 (2006.01); C12P 21/02 (2006.01);
U.S. Cl.
CPC ...
C12N 9/88 (2013.01); C12P 13/02 (2013.01); C07K 2319/00 (2013.01); C12P 21/02 (2013.01); C12Y 402/01084 (2013.01);
Abstract

The present invention provides a fused NHase with improved specific activity and stability, which relates to the field of genetic engineering. This invention provides a method of overexpressing a fused NHase inand producing a mutant NHase with improved stability and product tolerance. The invention provides a simple, efficient and safe method of making mutant NHase, and can produce a large amount of soluble NHases in a short period. The present invention makes a contribution to large-scale industrial production and further theoretical study of NHases.


Find Patent Forward Citations

Loading…