The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 20, 2018

Filed:

Jun. 16, 2016
Applicants:

Green Cross Corporation, Yongin-si, Gyeonggi-do, KR;

Medigenebio Corporation, Yongin-si, Gyeonggi-do, KR;

Inventors:

Thong-Gyu Jin, Seoul, KR;

Yo Kyung Chung, Yongin-si, KR;

Sang Hoon Paik, Yongin-si, KR;

Yoo Chang Park, Yongin-si, KR;

Jinwook Seo, Yongin-si, KR;

Yong Woon Choi, Yongin-si, KR;

Jong Mun Son, Yongin-si, KR;

Yong-Chul Kim, Yongin-si, KR;

Assignees:

GREEN CROSS CORPORATION, Yongin-Si, KR;

MediGeneBio Corporation, Yongin-Si, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/46 (2006.01); C12N 9/16 (2006.01); A61K 9/00 (2006.01); A61K 47/02 (2006.01); A61K 47/26 (2006.01);
U.S. Cl.
CPC ...
C12N 9/16 (2013.01); A61K 9/0019 (2013.01); A61K 38/465 (2013.01); A61K 47/02 (2013.01); A61K 47/26 (2013.01); C12Y 301/06013 (2013.01);
Abstract

A composition comprising recombinant iduronate-2-sulfatase (IDS) and a method for producing a purified recombinant IDS are provided. The glycosylation pattern and formylglycine content of the IDS composition are different from those of ELAPRASE® and have superior pharmaceutical efficacy and are safer than the conventional agent and thus can be effectively used for the therapy of Hunter syndrome.


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