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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9896518 B1

PDFFull Text
Date of Patent:
Feb. 20, 2018

Filed:

Sep. 10, 2013

Dilute filtration sterilization process for viscoelastic biopolymers

Applicant:

Bio-technology General (Israel) Ltd., Rehovot, IL;

Inventors:

Menakem Fuchs, Rishon Lezion, IL;

Dror Eyal, Nes Ziona, IL;

Yehuda Zelig, Nes Ziona, IL;

Assignee:

Bio-Technology General (Israel) Ltd., Rehovot, IL;

Attorney:

Fish & Richardson

Primary Examiner:

Shobha Kantamneni

Int. Cl.
CPC ...
A61K 31/715 (2006.01); A61K 47/00 (2006.01); C07H 5/06 (2006.01); C08B 37/08 (2006.01); C08B 37/00 (2006.01); C12P 19/26 (2006.01); A61K 31/728 (2006.01);
U.S. Cl.
CPC ...
C08B 37/0072 (2013.01); A61K 31/728 (2013.01); C08B 37/0003 (2013.01); C12P 19/26 (2013.01);
Abstract

Manufactured hyaluronic acid products are used in numerous surgical applications including viscoelastic supplementation for the treatment of osteoarthritis, however, traditional sterilization techniques result in the breakdown of such high molecular o weight viscoelastic biopolymers and are thus unsuitable. Disclosed are processes for obtaining concentrated sterile solutions of high molecular weight biopolymers such as hyaluronic acid. The processes include filter sterilization with a dilute preparation of the biopolymer, and concentration of the dilute filter sterilized biopolymer by ultrafiltration to a desired concentration.

Find Patent Forward Citations

Fuchs, Menakem. (2018). Dilute filtration sterilization process for viscoelastic biopolymers (U.S. Patent No. 9896518). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9896518

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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