The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 20, 2018

Filed:

Feb. 26, 2015
Applicant:

Centro DE Ingeniería Genética Y Biotecnología, Playa la Habana, CU;

Inventors:

Glay Chinea Santiago, Playa la Habana, CU;

Vivian Huerta Galindo, Playa la Habana, CU;

Alejandro Miguel Martín Dunn, Playa la Habana, CU;

Hilda Elisa Garay Pérez, Playa la Habana, CU;

Osvaldo Reyes Acosta, Playa la Habana, CU;

Viviana Falcón Cama, Playa la Habana, CU;

Dianne Pupo Gómez, Havana, CU;

Alexis Yero Díaz, Havana, CU;

Gabriel Jesús Márquez Perera, Playa la Habana, CU;

Mónica Sarría Núñez, Havana, CU;

Osmany Guirola Cruz, Havana, CU;

Rocío Garateix Suárez, Havana, CU;

Karen Alvarez Pérez, Havana, CU;

Sonia González Blanco, Playa la Habana, CU;

Mariela Vázquez Castillo, Playa la Habana, CU;

Luis Javier González López, Playa la Habana, CU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/10 (2006.01); C07K 7/08 (2006.01); C07K 14/00 (2006.01); A61K 38/16 (2006.01); A61K 47/42 (2017.01); A61K 47/69 (2017.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); A61K 38/10 (2013.01); A61K 38/16 (2013.01); A61K 47/42 (2013.01); A61K 47/6929 (2017.08); C07K 14/00 (2013.01); A61K 38/00 (2013.01); C07K 2319/21 (2013.01);
Abstract

The present invention discloses structurally constrained synthetic peptides that have been optimized for the formation of a beta hairpin structure. Said peptides are able to inhibit or attenuate Dengue virus (DENV) infections. The invention also discloses pharmaceutical compositions containing these synthetic peptides, which are useful for the prevention and/or treatment of DENV-caused infections. Likewise, the invention disclosed a method for treating infections caused by this virus.


Find Patent Forward Citations

Loading…