The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 20, 2018
Filed:
Oct. 20, 2016
Eolas Therapeutics, Inc., Carlsbad, CA (US);
Theodore M. Kamenecka, Palm Beach Gardens, FL (US);
Yuanjun He, Palm Beach Gardens, FL (US);
William Nguyen, Jupiter, FL (US);
Rong Jiang, Millersville, MD (US);
Xinyi Song, Bristol, PA (US);
Robert Jason Herr, Voorheesville, NY (US);
Qin Jiang, Latham, NY (US);
EOLAS THERAPEUTICS, INC., Carlsbad, CA (US);
Abstract
The present invention is directed to compounds that modulate the bioactivity of an orexin receptor such as OXor OX, or both; to pharmaceutical compositions and combinations comprising a compound of the invention; to methods of treatment of malconditions in patients wherein modulation of an orexin receptor is medically indicated; and to methods of preparation of compounds of the invention. For example, orexin receptor-modulatory compounds of the present invention can be used in treatment of an eating disorder, obesity, alcoholism or an alcohol-related disorder, drug abuse or addiction including addiction to cocaine, opiates, amphetamines, or nicotine, a sleep disorder, a cognitive dysfunction in a psychiatric or neurologic disorder, depression, anxiety, panic disorder, schizophrenia, Alzheimer's disease, Parkinson's disease, Huntington's chorea, headache, migraine, pain, gastrointestinal diseases, epilepsy, inflammations, immune-related diseases, endocrine-related diseases, cancer, hypertension, behavior disorder, mood disorder, manic depression, dementia, sex disorder, psychosexual disorder, or renal disease.