The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 20, 2018
Filed:
Sep. 17, 2014
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Andrew J. Cooke, West Point, PA (US);
Craig A. Stump, West Point, PA (US);
Xu-fang Zhang, Drescher, PA (US);
Chun Sing LI, Shanghai, CN;
Qinghua Mao, Shanghai, CN;
Andrew J. Cooke, Doylestown, PA (US);
Craig A. Stump, Pottstown, PA (US);
Xu-Fang Zhang, Dresher, PA (US);
Chun Sing Li, Shanghai, CN;
Qinghua Mao, Shanghai, CN;
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
The present invention is directed to benzyl urea compounds of formula (I) which are tropomyosin-related kinase (Trk) family protein kinase inhibitors, and hence may be useful in the treatment of pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder associated with abnormal activities of nerve growth factor (NGF) receptor Trk-A, Trk-B and/or Trk-C.