The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 20, 2018
Filed:
Dec. 18, 2015
Ignyta, Inc., San Diego, CA (US);
Cancer Research Technology Limited, London, GB;
Henry J. Breslin, Lansdale, PA (US);
Bruce D. Dorsey, Ambler, PA (US);
Benjamin J. Dugan, Glen Mills, PA (US);
Robert L. Hudkins, Chester Springs, PA (US);
Eugen F. Mesaros, Wallingford, PA (US);
Gregory R. Ott, Media, PA (US);
Craig A. Zificsak, Dowingtown, PA (US);
Allison L. Zulli, Wayne, PA (US);
Ming Tao, Maple Glen, PA (US);
Katherine M. Fowler, Caversham, GB;
Emma L. Morris, Biggleswade, GB;
Gregoire A. Pave, London, GB;
Jonathan R. A. Roffey, Reading, GB;
Nathaniel J. T. Monck, Ascot, GB;
Christelle N. Soudy, London, GB;
Ikeoluwa Olowoye, Hemel Hempstead, GB;
CANCER RESEARCH TECHNOLOGY LIMITED, London, GB;
Abstract
The present application provides a compound of formula (I) or a salt thereof, wherein R, R, R, G, and X are as defined herein. This application further describes compositions comprising the same. Compounds of formula (I) and their salts have aPKC inhibitory activity, and may be used to treat proliferative diseases.