The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 20, 2018
Filed:
Sep. 28, 2014
Jiangsu Jibeier Pharmaceutical Co. Ltd., Jiangsu, CN;
Zhenjiang San an Pharmaceutical Co. Ltd., Jiangsu, CN;
Zhongyi Geng, Jiangsu, CN;
Xinghai Chen, Jiangsu, CN;
Parker Aulma, Jiangsu, CN;
Wei Peng, Jiangsu, CN;
Jiangsu Jibeier Pharmaceutical Co., Ltd., Jiangsu, CN;
Zhenjiang San An Pharmaceutical Co., Ltd., Jiangsu, CN;
Abstract
The present disclosure provides a deuterium substituted 1-[2-(2,4-dimethyl-phenylsulfanyl)-phenyl]piperazine compound with a structure represented by formula (I) or a derivative thereof, a pharmaceutical composition containing the compound or the derivative thereof, and an application of the compound or the derivative thereof in preparing drugs. The compound can reduce oxidative metabolism thereof, increase the drug concentration in blood and the effective bioavailability, so as to lower the dosage and reduce the toxicity and other side effects. The deuterium 1-[2-(2,4-dimethyl-phenylsulfanyl)-phenyl]piperazine compound and its derivative thereof provided by the present disclosure can be used to treat related diseases such as affective disorders, depression and anxiety.