The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 20, 2018

Filed:

Mar. 09, 2015
Applicant:

Bio-rad Laboratories, Inc., Hercules, CA (US);

Inventors:

Clayton T. McKee, Davis, CA (US);

William Strong, El Cerrito, CA (US);

Assignee:

Bio-Rad Laboratories, Inc., Hercules, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/543 (2006.01); B01L 3/00 (2006.01); G01N 27/447 (2006.01); C12Q 1/68 (2018.01);
U.S. Cl.
CPC ...
B01L 3/502738 (2013.01); C12Q 1/6806 (2013.01); G01N 27/44717 (2013.01); G01N 27/44739 (2013.01); G01N 33/54366 (2013.01); B01L 2200/0605 (2013.01); B01L 2200/0642 (2013.01); B01L 2300/045 (2013.01); B01L 2300/047 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0874 (2013.01); B01L 2400/0415 (2013.01); B01L 2400/0418 (2013.01); B01L 2400/0421 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/065 (2013.01);
Abstract

Devices, systems, methods, and kits are provided for performing separation, immobilization, blotting, and/or detection of analytes from biological samples. In some embodiments, the devices are constructed from two solid substrates with surfaces in contact. The devices include a plurality of channels formed from indentations in these surfaces. The indentations can be aligned with each other across the interface between the substrates, and realigned by shifting or sliding one substrate relative to the other. In some embodiments, the devices are constructed from three layers of a solid substrate. A separation channel in the middle layer of the device is first used for analyte separation. The middle layer can then be slid relative the top and/or bottom layer, thereby aligning the separation channel with a blotting membrane. Analytes can then be transferred to the membrane using electrodes in the top and bottom layers.


Find Patent Forward Citations

Loading…