The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 20, 2018

Filed:

Apr. 10, 2008
Applicants:

Arturo Reyes, Oxfordshire, GB;

Adrian Hill, Oxfordshire, GB;

Geraldine O'hara, Oxfordshire, GB;

Stefano Colloca, Rome, IT;

Riccardo Cortese, Rome, IT;

Inventors:

Arturo Reyes, Oxfordshire, GB;

Adrian Hill, Oxfordshire, GB;

Geraldine O'Hara, Oxfordshire, GB;

Stefano Colloca, Rome, IT;

Riccardo Cortese, Rome, IT;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/015 (2006.01); A61P 35/00 (2006.01); A61P 33/06 (2006.01); C12N 15/861 (2006.01); A61P 37/04 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
A61K 39/015 (2013.01); C12N 15/86 (2013.01);
Abstract

The invention provides recombinant adenoviral vectors which are capable of eliciting immunity against the pre-erythrocytic stage of the life cycle of the malaria parasite. In particular, the invention provides a recombinant, replication deficient simian adenoviral vector which encodes an antigen comprising the thrombospondin-related adhesion protein (TRAP), and also immunogenic compositions (e.g. vaccines) comprising the vector and methods of using such compositions.


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