The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 20, 2018

Filed:

Jul. 03, 2013
Applicant:

University-industry Cooperation Group of Kyung Hee University, Gyeonggi-do, KR;

Inventors:

Jin Ju Kim, Gyeonggi-do, KR;

Eun Jung Ko, Seoul, KR;

Eui Jeoung Lee, Seoul, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 36/53 (2006.01); A61K 36/79 (2006.01); A61K 36/64 (2006.01); A61K 36/185 (2006.01); A61K 38/20 (2006.01); A61K 36/8965 (2006.01); A61K 36/539 (2006.01); A61K 36/804 (2006.01); A61K 36/904 (2006.01); A61K 36/65 (2006.01); A61K 36/73 (2006.01); A61K 35/618 (2015.01); A61K 36/84 (2006.01); A61K 36/738 (2006.01); A61K 38/19 (2006.01);
U.S. Cl.
CPC ...
A61K 38/204 (2013.01); A61K 35/618 (2013.01); A61K 36/539 (2013.01); A61K 36/65 (2013.01); A61K 36/73 (2013.01); A61K 36/738 (2013.01); A61K 36/79 (2013.01); A61K 36/804 (2013.01); A61K 36/84 (2013.01); A61K 36/8965 (2013.01); A61K 36/904 (2013.01); A61K 38/19 (2013.01); A61K 38/191 (2013.01); A61K 38/2006 (2013.01);
Abstract

The present invention relates to a pharmaceutical composition, which contains a mixture of extracts of Stemonae Radix, Asparagi Tuber, Scutellariae Radix, Schisandrae Fructus, Rehmanniae Radix Preparata, Armeniacae Semen, and Moutan Cortex Radicis, for suppressing the occurrence of inflammatory bowel diseases due to cigarette smoke, a method for preventing or treating inflammatory bowel diseases, a method for suppressing the expression of inflammatory cytokines by using the composition, and to a food composition, which contains a mixture of extracts of Stemonae Radix, Asparagi Tuber, Scutellariae Radix, Schisandrae Fructus, Rehmanniae Radix Preparata, Armeniacae Semen, and Moutan Cortex Radicis, for preventing or ameliorating inflammatory bowel diseases due to cigarette smoke. The pharmaceutical composition, according to the present invention, contains the mixture of extracts of Stemonae Radix, Asparagi Tuber, Scutellariae Radix, Schisandrae Fructus, Rehmanniae Radix Preparata, Armeniacae Semen, and Moutan Cortex Radicis, thereby reducing the level of MMP12 expression that is known to destroy IL-1β, TNF-α, IL-6 and MCP-1, which are inflammatory cytokines that accompany the inflammatory bowel diseases, elastin, and collagen, and thus can be widely used in developing a safe and effective inflammatory bowel disease treating agent.


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