The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 20, 2018
Filed:
May. 02, 2016
Applicant:
Galapagos NV, Mechelen, BE;
Inventors:
Steven Emiel Van Der Plas, Mechelen, BE;
Hans Kelgtermans, Mechelen, BE;
Sébastien Jean Jacques Cédric Dropsit Montovert, Mechelen, BE;
Sébastien Laurent Xavier Martina, Mechelen, BE;
Martin James Inglis Andrews, Mechelen, BE;
Assignee:
Galapagos NV, Mechelen, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/675 (2006.01); A61K 31/381 (2006.01); C07D 495/04 (2006.01); C07F 9/6561 (2006.01); A61K 31/38 (2006.01); C07F 7/08 (2006.01); C07F 9/09 (2006.01); A61K 31/4025 (2006.01); A61K 31/4155 (2006.01); A61K 31/4162 (2006.01); A61K 31/4178 (2006.01); A61K 31/4196 (2006.01); A61K 31/422 (2006.01); A61K 31/427 (2006.01); A61K 31/437 (2006.01); A61K 31/4436 (2006.01); A61K 31/497 (2006.01); A61K 31/519 (2006.01); A61K 31/53 (2006.01); A61K 31/436 (2006.01); A61K 31/501 (2006.01); A61K 31/517 (2006.01);
U.S. Cl.
CPC ...
A61K 31/381 (2013.01); A61K 31/38 (2013.01); A61K 31/4025 (2013.01); A61K 31/4155 (2013.01); A61K 31/4162 (2013.01); A61K 31/4178 (2013.01); A61K 31/4196 (2013.01); A61K 31/422 (2013.01); A61K 31/427 (2013.01); A61K 31/436 (2013.01); A61K 31/437 (2013.01); A61K 31/4436 (2013.01); A61K 31/497 (2013.01); A61K 31/501 (2013.01); A61K 31/517 (2013.01); A61K 31/519 (2013.01); A61K 31/53 (2013.01); A61K 31/675 (2013.01); C07D 495/04 (2013.01); C07F 7/0812 (2013.01); C07F 9/091 (2013.01); C07F 9/6561 (2013.01);
Abstract
The present invention discloses compounds according to Formula I: wherein Ris as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment cystic fibrosis by administering a compound of the invention.