The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 20, 2018

Filed:

Aug. 22, 2014
Applicants:

Sinochem Corporation, Beijing, CN;

Shenyang Research Institute of Chemical Industry Co., Ltd., Shenyang, Liaoning, CN;

Inventors:

Changling Liu, Liaoning, CN;

Aiying Guan, Liaoning, CN;

Xiaoping Yang, Liaoning, CN;

Baoshan Chai, Liaoning, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/366 (2006.01); A61K 31/415 (2006.01); A61K 31/505 (2006.01); A61K 31/216 (2006.01);
U.S. Cl.
CPC ...
A61K 31/366 (2013.01); A61K 31/216 (2013.01); A61K 31/415 (2013.01); A61K 31/505 (2013.01);
Abstract

Disclosed are applications of substituent benzyloxy group containing ether compounds represented by general formula I for preparing antitumor drugs. The definition of the substituent groups in the formula I are provided in the specification. The compounds having general formula I have desirable antitumor activity, particularly, and have excellent activity against leukemia strain HL-60, lung cancer A549, H157, H460, H520, bladder cancer T24, J82, prostate cancer LNCap, PC-3, rectal cancer HCT8, HCT116, RkO and the like.


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