The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 20, 2018
Filed:
Jul. 07, 2014
Applicant:
Nicox Science Ireland, Dublin, IE;
Inventors:
Ennio Ongini, Segrate, IT;
Nicoletta Almirante, Milan, IT;
Laura Storoni, Cesano Maderno, IT;
Elena Bastia, Milan, IT;
Assignee:
NICOX SCIENCE IRELAND, Dublin, IE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 57/00 (2006.01); A61K 31/66 (2006.01); A61K 31/22 (2006.01); A61K 45/06 (2006.01); A61K 9/00 (2006.01); C07C 203/04 (2006.01); A61K 31/215 (2006.01);
U.S. Cl.
CPC ...
A61K 31/22 (2013.01); A61K 9/0048 (2013.01); A61K 31/215 (2013.01); A61K 45/06 (2013.01); C07C 203/04 (2013.01);
Abstract
The present invention relates to compositions comprising a 4-nitrooxybutan-1-ol alkyl ester as nitric oxide donor. More specifically, the invention relates to compositions comprising 4-nitrooxybutan-1-ol alkyl ester as a nitric oxide donor and an ophthalmic drug, useful in controlling elevated intraocular pressure associated with glaucoma or ocular hypertension associated with other diseases or conditions. The invention is also directed to methods of controlling intraocular pressure utilizing said compositions.