The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 13, 2018

Filed:

Nov. 11, 2015
Applicant:

Nestec S.a., Vevey, CH;

Inventors:

Fabiyola Selvaraj, San Diego, CA (US);

Fred Princen, La Jolla, CA (US);

Sharat Singh, Rancho Santa Fe, CA (US);

Assignee:

Nestec S.A., Vevey, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/04 (2006.01); C07D 495/04 (2006.01); C07D 519/00 (2006.01); C07K 16/44 (2006.01); G01N 33/68 (2006.01); C07K 16/12 (2006.01); C07K 16/26 (2006.01); G01N 33/94 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6893 (2013.01); C07D 495/04 (2013.01); C07D 498/04 (2013.01); C07D 519/00 (2013.01); C07K 16/12 (2013.01); C07K 16/26 (2013.01); C07K 16/44 (2013.01); G01N 33/6812 (2013.01); G01N 33/942 (2013.01); C07K 2317/33 (2013.01); G01N 2800/065 (2013.01); G01N 2800/52 (2013.01);
Abstract

The present invention provides antibodies and methods for preparing antibodies to metabolites in the serotonin, tryptophan, kynurenine pathways. The prepared antibodies have low cross-reactivity to related metabolites, and are useful reagents for specific and sensitive immunoassays The present invention also provides stable derivatives of various metabolites and short chain fatty acids. The derivative can be conjugated to a biomolecule such as a carrier protein and combined with an adjuvant to stimulate an immune response. The derivatives can also be conjugated to other biomolecules.


Find Patent Forward Citations

Loading…