The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 13, 2018
Filed:
Dec. 05, 2011
Applicants:
Massimo Bocchi, Sasso Marconi, IT;
Roberto Guerrieri, Bologna, IT;
Inventors:
Massimo Bocchi, Sasso Marconi, IT;
Roberto Guerrieri, Bologna, IT;
Assignee:
CELLPLY S.R.L., Bologna, IT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 1/40 (2006.01); G01N 33/50 (2006.01); G01N 15/14 (2006.01); B01L 3/00 (2006.01); B03C 5/00 (2006.01); B03C 5/02 (2006.01); G01N 27/447 (2006.01); C12M 1/32 (2006.01);
U.S. Cl.
CPC ...
G01N 15/1404 (2013.01); B01L 3/5088 (2013.01); B01L 3/50273 (2013.01); B01L 3/502792 (2013.01); B03C 5/005 (2013.01); B03C 5/022 (2013.01); B03C 5/026 (2013.01); G01N 1/4077 (2013.01); G01N 15/1484 (2013.01); G01N 27/44791 (2013.01); G01N 33/50 (2013.01); G01N 33/5005 (2013.01); B01L 2200/0652 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0829 (2013.01); B01L 2300/0864 (2013.01); B01L 2400/0424 (2013.01); B03C 2201/26 (2013.01); C12M 23/12 (2013.01); G01N 2015/149 (2013.01); G01N 2015/1415 (2013.01); G01N 2015/1481 (2013.01);
Abstract
An inverted microwell () provides rapid and efficient microanalysis system () and method for screening of biological particles (), particularly functional analysis of cells on a single cell basis. The use of an inverted open microwell system () permits identification of particles, cells, and biomolecules that may be combined to produce a desired functional effect also functional screening of secreted antibody therapeutic activity as well as the potential to recover cells and fluid, and optionally expand cells, such as antibody secreting cells, within the same microwell.