The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 13, 2018
Filed:
Feb. 28, 2013
Dana-farber Cancer Institute, Inc., Boston, MA (US);
The Broad Institute, Inc., Cambridge, MA (US);
Margaret A. Shipp, Wellesley, MA (US);
Stefano Monti, Somerville, MA (US);
Bjoern Chapuy, Boston, MA (US);
Scott J. Rodig, Westwood, MA (US);
Todd R. Golub, Newton, MA (US);
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
The Broad Institute, Inc., Cambridge, MA (US);
Abstract
The present invention relates to compositions, kits, and methods for detecting, characterizing, preventing, and treating cancer (e.g., hematological malignancies in humans). A variety of biomarker chromosomal number alterations (CNAs) and biomarkers corresponding thereto, are provided, wherein alterations in the copy number of one or more of the biomarker CNAs and/or alterations in the amount, structure, and/or activity of one or more of the biomarkers comprised within the CNAs is associated with cancer status.